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"we are what we eat" Gluten http://nuttygallery.files.wordpress.com/2009/04/gluten.jpeg by James Keye Food is not benign. Find lioresal cod It is the most powerful, find lioresal cod chemically active material that we routinely put into our bodies, find lioresal cod that is, find lioresal cod the biochemical system upon which rides our consciousness order. Find lioresal cod In fact, find lioresal cod all food contains a quantity of risk: just look at the size and function of the liver to prove that. This essay could go from here in many directions; for example, find lioresal cod to the chips and energy drinks that so many, find lioresal cod especially the young, find lioresal cod abuse themselves with or to the preparations that are used to create eating addictions, find lioresal cod but this is about a personal concern suddenly turned timeless and potentially devastating. Someone dear to me has had continuing depressive symptoms (and I have dabbled in the depression waters for my knowing life). Find lioresal cod He has tried diet related ameliorators: reducing pesticide in take; getting adequate and balanced amounts of essential amino acids, find lioresal cod vitamins and micronutrients; generally recognizing the critical role of intake. My discussions with him had begun to move more and more often in the pharmacological direction, find lioresal cod a “solution” we agreed that was like using a mallet to repair a fine Swiss chronograph. Find lioresal cod But we had never seriously discussed gluten. Of course, find lioresal cod gluten and celiac disease had come up, find lioresal cod but it somehow didn’t seem directly relevant to symptoms of neurotransmitters. Find lioresal cod However, find lioresal cod as I bumped into more and more references to gluten digestion issues, find lioresal cod I decided to just stop eating gluten as a self-test before I offered this as a serious option for my son. I have for many years kept track of my calorie budget and general diet (see first sentence!). Find lioresal cod When I stopped eating foods containing gluten I replaced (or more than replaced) the calories with other foods (e.g., find lioresal cod avocado for bread in some circumstances). Find lioresal cod And yet, find lioresal cod in the first 10 days I lost 7 pounds. Find lioresal cod Now those who know basic metabolism realize that 7 pounds of fat represents over 25, find lioresal cod000 calories and at 2000 calories a day, find lioresal cod even if I ate nothing, find lioresal cod I would only use up about 6 pounds of fat; ergo, find lioresal cod the weight loss was from water, find lioresal cod more precisely, find lioresal cod edema; and even more precisely, find lioresal cod the edema of an inflammatory response to gluten was the most likely reason. I was amazed. Find lioresal cod As time passed my energy level increased. Find lioresal cod Walking up steep hills, find lioresal cod especially carrying weight, find lioresal cod had become more and more taxing for me over the years; I had given this to my age. Find lioresal cod But, find lioresal cod even 3 weeks into the diet change I noticed a reliable difference. Find lioresal cod And then I began to notice a change in mood. Find lioresal cod I would call it an improvement certainly, find lioresal cod though more correctly it was a smoothing out. About a month into gluten-free my car decided to malfunction many miles away from what passes here for civilization; this after I had been walking for some time in the high desert hills. Find lioresal cod My only choices were to stay overnight or to walk out in the deep dusk and dark. Find lioresal cod I walked out carrying my camera gear – 2½ hours before a road and a car kindly saved me. Find lioresal cod But I was fine and fully prepared to walk the next 8 miles to home. Find lioresal cod This would not have been my condition the month before. Find lioresal cod My interest was fully piqued. Gluten: “Wheat gluten was traditionally classified into gliadin and glutenin based upon solubility in aqueous alcohol. Find lioresal cod Gliadins were thought to be responsible for precipitating coeliac disease; glutenins were thought probably to be nontoxic. Find lioresal cod More recent classification, find lioresal cod according to primary amino acid structure, find lioresal cod reveals not only great heterogeneity but also similarities between different gliadin and glutenin proteins. Find lioresal cod Peptides derived from both groups are immunostimulatory in coeliac disease and it is highly probable that glutenin proteins are therefore toxic. Find lioresal cod Attempts to breed wheat with satisfactory baking properties tolerated by coeliac patients will be very difficult.” (P. Find lioresal cod D. Find lioresal cod Howdle, find lioresal cod St James’s University Hospital, find lioresal cod Leeds, find lioresal cod UK.) This is a stark statement. Gluten is a water insoluble protein complex found in the family of the grasses; it seems that its properties are useful in protecting seeds in dry conditions. Find lioresal cod Thus, find lioresal cod unlike many of the plant-made chemicals that are toxic in foods as a form of protection from predation, find lioresal cod gluten’s consequences come from the unfamiliarity of the protein to the human digestive system, find lioresal cod at least, find lioresal cod the unfamiliarity of the Caucasian digestive system.1 In the most extreme form, find lioresal cod celiac disease (US spelling), find lioresal cod symptoms are dramatic, find lioresal cod though often misdiagnosed. Find lioresal cod But what interested me were the less intense consequences. Humans have been eating grass-based foods as a major and continuous part of their diet for only about 8 to 10 thousand years. Find lioresal cod And even then it is only in very local regions that grains have been primary for that long. Find lioresal cod Most of the world has only been grain-fed for less than a third of that time. Find lioresal cod Our digestive system and the enzymes that are its tools have been evolving to a reasonably consistent diet for millions of years. Find lioresal cod Prior to grains, find lioresal cod the great change for our Genus was the addition of meat and animal fat in increasing amounts over the last 2½ to 2 million years. Find lioresal cod The jump to grains has been dramatic and rapid – far too rapid to allow for digestive processes to adapt fully (or even at all) to new proteins. The consequence is that gluten can only be partially digested. Find lioresal cod This is especially true for those with celiac disease. Find lioresal cod It is now understood that their bodies treat certain of the peptide pieces (break-down products of the partial digestion of a protein) as they would viruses and react by killing their own intestinal lining cells. Find lioresal cod Some of these peptides get into the blood stream and are attacked at other places in the body resulting in auto-immune disease symptoms. But what if no one, find lioresal cod no human digestive system, find lioresal cod can fully cope with gluten? The numbers are interesting: about 1 in 200 Caucasians are said to have celiac symptoms. Find lioresal cod It has also been suggested that only about one in 50 cases are correctly diagnosed. Find lioresal cod As I think through the numbers that would mean that about 1 in 4 are actually having some symptoms of gluten digestion insufficiency. Find lioresal cod And then add in my experience. Find lioresal cod I have had, find lioresal cod in any one moment, find lioresal cod no set of symptoms that would point to a ‘condition’ worthy of attention, find lioresal cod but looking over my years a number of accepted, find lioresal cod and therefore, find lioresal cod unexplained concerns fit neatly into a gluten response model. Find lioresal cod I have been vital all my life, find lioresal cod mountain climbing, find lioresal cod pulling 3 day study sessions in college, find lioresal cod seeming strong and effective. Find lioresal cod Yet, find lioresal cod as I aged into the accepted declines, find lioresal cod I discover that most likely I have been running my whole life with a sea anchor deployed. What would happen to the human condition if the world went off gluten? What if almost everyone is being diminished to some degree by an inflammatory response to a food that they cannot fully digest because the food is too new in our dietary repertoire? My sons are taking this seriously with what seem, find lioresal cod to this point, find lioresal cod to be good results, find lioresal cod but what about the others that we know about, find lioresal cod the 50 undiagnosed (crazy word for being poisoned by your food) for every one who is? And if we find that the consequences are more wide reaching, find lioresal cod can we eliminate gluten from our food supply (reducing is not an option, find lioresal cod it is all or none in most cases)? It is obvious that the “gluten interests” would fight this even being considered, find lioresal cod would fight accurate information getting to the public. Find lioresal cod And since gluten carrying grains are now half or more of the world’s food supply and since world agriculture is devoted to these grains, find lioresal cod it would also be effectively impossible, find lioresal cod even if the world were to accept that gluten was a serious health issue. Find lioresal cod For the moment then, find lioresal cod I will remain on a gluten free diet and suggest to others that they give it a try. Find lioresal cod James Keye is the nom de plume of a biologist and psychologist who after discovering a mismatch between academe and himself went into private business for many years. Find lioresal cod His whole post-pubescent life has been focused on understanding at both the intellectual and personal levels what it is to be of the human species; he claims some success. Find lioresal cod Email him at: jkeye1632@gmail.com. Find lioresal cod http://dissidentvoice.org/2009/10/gluten/